Cannabis Extracts have reduced the number of (virus) receptors by 73 per cent making people more resistant coronavirus infection

Cannabis extracts are showing potential in making people more resistant to the novel coronavirus, says researcher Dr. Igor Kovalchuk, leading the study.

After sifting through 400 cannabis strains, researchers are concentrating on about a dozen that show promising results in ensuring less fertile ground for the potentially lethal virus to take root, said biological scientist Kovalchuk.

“A number of them have reduced the number of these (virus) receptors by 73 per cent, the chance of it getting in is much lower,” said Kovalchuk.

“If they can reduce the number of receptors, there’s much less chance of getting infected.”

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Employing cannabis Sativa strains over the past three months, the researcher said the effective balance between cannabis components THC and CBD – the latter more typically associated with medical use – is still unclear in blocking the novel coronavirus.

“It will take a long time to find what the active ingredient is – there may be many,” said Kovalchuk, whose Pathway RX is owned partly by licensed cannabis producer Sundial Growers and partnered with cannabis researcher Swysh.

But it’s generally the anti-inflammatory properties of CBD – found in products like Vibes CBD oil – that have shown most promise, according to the researchers.

“We focus more on the higher CBD because people can take higher doses,” said Kovalchuk.

The study which has been using artificial human 3-D tissue models has been seeking ways to hinder the highly contagious novel coronavirus from finding a host in the lungs, intestines, and oral cavity.

If successful, the work on cannabis extracts could find practical medical use in the form of mouth wash, gargle, inhalants or gel caps, said Kovalchuk. Though people enjoying standard cannabis products such as baked edibles may still take it that way in order to feel the benefits.

For medical applications of their findings, the absence of clinical trials remains a barrier, and funding from an increasingly cash-strapped cannabis industry apparently isn’t there to fuel that.

“We have clinicians who are willing to work with us but for a lot of companies in the cannabis business, it’s significant cash that they can’t afford,” he said.

The scientist emphasized the findings wouldn’t lead to a vaccine – something “less specific and precise” but nonetheless another possible weapon against COVID-19.

“The extracts of our most successful and novel high CBD C sativa lines, pending further investigation, may become a useful and safe addition to the treatment of COVID-19 as an adjunct therapy,” said Kovalchuk.

“Given the current dire and rapidly evolving epidemiological situation, every possible therapeutic opportunity and avenue must be considered.”

Researchers have begun clinical trials of CBD as a treatment to repair cells damaged by COVID-19 by using its anti-inflammatory abilities.

It’s thought CBD could enhance the traditional effect of steroids in such treatment of patients in life-threatening condition and also bolster the immune system.

“Our work could have a huge influence – there aren’t many drugs that have the potential of reducing infection by 70 to 80 per cent,” he said.