According to Charlie’s manager, he died from leukemia Wednesday morning in a NYC hospital. He’d been going undergoing chemotherapy.

Charlie famously co-starred on “Chappelle’s Show” in some of Dave’s most memorable skits … including the nights Charlie partied with Rick James and Prince.

Charlie also co-wrote some of Eddie Murphy’s movies, like “Norbit” and “Vampire in Brooklyn.” He co-starred in “Are We There Yet?,” “The Boondocks” and “Black Jesus.”

He recently toured with Cedric the Entertainer, Eddie Griffin, George Lopez and D.L. Hughley on “The Comedy Get Down.”

Charlie’s wife, Tisha Taylor Murphy, died in 2009 from cervical cancer. They had 2 children, and he had another from a previous relationship.

Charlie was 57.

#RIP tmz